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Figure 2 | Neural Development

Figure 2

From: Axon fasciculation in the developing olfactory nerve

Figure 2

Homotypic axon segregation occurs by E12. Sagittal sections of CD1 embryos. (A, B) NQO1 (green)/OCAM (red). NQO1+ cells are clustered caudally, mostly within the OCAM+ region of the nerve. (C-E) NRP-1 (green)/NCAM (red): (C) lateral section - open arrowhead indicates NRP-1+ region; (D) medial section; (E) three-dimensional reconstruction from the lateral side of the nerve. The asterisk indicates the central region of the nerve devoid of NRP-1 staining. An orientation compass is shown in (B), for (A-D) and in (E). Scale bar shown in (D) = 50 μm in (A, B) and 100 μm in (C, D).

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